INVITRO SYNERGY TESTING OF 9 ANTIMICROBIAL COMBINATIONS AGAINST LISTERIA-MONOCYTOGENES

被引：17

作者：

MACGOWAN, AP

HOLT, HA

REEVES, DS

机构：

[1] Department of Microbiology, Southmead Hospital, Westbury-on-Trym, Bristol

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1990年 / 25卷 / 04期

关键词：

D O I：

10.1093/jac/25.4.561

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In-vitro antimicrobial synergy against Listeria monocytogenes was assessed using nine combinations in chequerboard (bacteriostatic) tests and time-kill (bactericidal) studies. Ampicillin/gentamicin and trimethoprim/suiphamethoxazole were the most synergistic combinations in bacteristatic tests, whereas gentamicin with ampicillin, trimethoprim or vancomycin and trimethoprim/sulphamethoxazole were the most synergistic in bactericidal tests. Gentamicin-containing combinations were most effective at killing L. monocytogenes and those containing rifampicin least effective. © 1990 The British Society for Antimicrobial Chemotherapy.

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页码：561 / 566

页数：6

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