MICROBIOLOGICAL EVALUATION OF THE EFFICACY OF CHLORHEXIDINE IN A SUSTAINED-RELEASE DEVICE FOR DENTIN STERILIZATION

被引:52
作者
HELING, I
SOMMER, M
STEINBERG, D
FRIEDMAN, M
SELA, MN
机构
[1] Department of Endodontics, The Hebrew University-Hadassah School of Dental Medicine, Jerusalem
[2] Department of Pharmacy, School of Pharmacy, Hebrew University, Hebrew University-Hadassah School of Dental Medicine, Jerusalem
[3] Department of Oral Eiology, Hebrew University-Hadassah School of Dental Medicine, Jerusalem
关键词
CALCIUM HYDROXIDE; CAMPHORATED MONOCHLOROPHENOL; CHLORHEXIDINE; ROOT CANAL MEDICATION;
D O I
10.1111/j.1365-2591.1992.tb00943.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The aim of this in-vitro study was to evaluate the effect of chlorhexidine in solution and in a sustained-release device as an intracanal medication. Hollow cylindrical dentine specimens prepared from bovine incisors were incubated with Streptococcus faecalis for a period of 3 weeks. The intracanal medicaments tested were 0.2% chlorhexidine gluconate solution (CH), chlorhexidine in a sustained-release device (1.2 mg) (SRD), camphorated paramonochlorophenol (CMCP), and a control (no medication). Each medicament was introduced into the lumen of one dentine specimen and incubated for 5 min, 24 h, 48 h or 7 days at 37-degrees-C. The bacteriological samples were taken by shaving the dentine inside the lumen with dental burs ranging in size from ISO 023-033. The dentine powder was collected in test-tubes containing growth medium and incubated for 24 h. The optical density of the medium was recorded by means of a spectrophotometer at a wavelength of 540 nm. There was a statistically significant difference between the control group and all the medicaments tested.
引用
收藏
页码:15 / 19
页数:5
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