REGULATION OF PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA IN MONOCYTES STIMULATED BY THE 30-KILODALTON ANTIGEN OF MYCOBACTERIUM-TUBERCULOSIS

被引：13

作者：

AVERILL, L

TOOSSI, Z

AUNG, H

BOOM, WH

ELLNER, JJ

机构：

来源：

INFECTION AND IMMUNITY | 1995年 / 63卷 / 08期

关键词：

D O I：

10.1128/IAI.63.8.3206-3208.1995

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The 30-kDa secreted antigen of Mycobacterium tuberculosis was a strong inducer of tumor necrosis factor alpha in human monocytes. Our findings suggest that tumor necrosis factor alpha production mag be up-regulated at both the posttranscriptional and transcriptional levels. Regulation at the posttranscriptional level probably reflects enhanced translational efficiency.

引用

页码：3206 / 3208

页数：3

共 15 条

[1] AGGARWAL BB, 1985, J BIOL CHEM, V260, P2345
[2] PROTEINS RELEASED FROM MYCOBACTERIUM-TUBERCULOSIS DURING GROWTH
ANDERSEN, P
ASKGAARD, D
LJUNGQVIST, L
BENNEDSEN, J
HERON, I
[J]. INFECTION AND IMMUNITY, 1991, 59 (06) : 1905 - 1910
[3] AUNG T, UNPUB
[4] 1,25 DIHYDROXYVITAMIN-D3-DEPENDENT INHIBITION OF GROWTH OR KILLING OF MYCOBACTERIUM-AVIUM COMPLEX IN HUMAN MACROPHAGES IS MEDIATED BY TNF AND GM-CSF
BERMUDEZ, LEM
YOUNG, LS
GUPTA, S
[J]. CELLULAR IMMUNOLOGY, 1990, 127 (02) : 432 - 441
[5] CACHECTIN AND TUMOR-NECROSIS-FACTOR AS 2 SIDES OF THE SAME BIOLOGICAL COIN
BEUTLER, B
CERAMI, A
[J]. NATURE, 1986, 320 (6063) : 584 - 588
[6] GAN H, 1993, J IMMUNOL, V150, P2892
[7] ENHANCEMENT OF INTRACELLULAR GROWTH OF MYCOBACTERIUM-TUBERCULOSIS IN HUMAN MONOCYTES BY TRANSFORMING GROWTH-FACTOR-BETA-1
HIRSCH, CS
YONEDA, T
AVERILL, L
ELLNER, JJ
TOOSSI, Z
[J]. JOURNAL OF INFECTIOUS DISEASES, 1994, 170 (05) : 1229 - 1237
[8] PROTECTIVE IMMUNITY AGAINST TUBERCULOSIS INDUCED BY VACCINATION WITH MAJOR EXTRACELLULAR PROTEINS OF MYCOBACTERIUM-TUBERCULOSIS
HORWITZ, MA
LEE, BWE
DILLON, BJ
HARTH, G
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (05) : 1530 - 1534
[9] THE INDUCING ROLE OF TUMOR NECROSIS FACTOR IN THE DEVELOPMENT OF BACTERICIDAL GRANULOMAS DURING BCG INFECTION
KINDLER, V
SAPPINO, AP
GRAU, GE
PIGUET, PF
VASSALLI, P
[J]. CELL, 1989, 56 (05) : 731 - 740
[10] A NOVEL FORM OF TNF/CACHECTIN IS A CELL-SURFACE CYTO-TOXIC TRANSMEMBRANE PROTEIN - RAMIFICATIONS FOR THE COMPLEX PHYSIOLOGY OF TNF
KRIEGLER, M
PEREZ, C
DEFAY, K
ALBERT, I
LU, SD
[J]. CELL, 1988, 53 (01) : 45 - 53

← 1 2 →