HIGH-PERFORMANCE AFFINITY-CHROMATOGRAPHY FOR ANALYSIS OF HUMAN ANTITHROMBIN-III

Antythrombin III (AT III) is one of the most important regulators of the coagulation system. Improper concentration of AT III in blood is a great risk and often leads to thrombotic complications. In routine laboratories there is a choice between two types of methods (functional and immunology) of AT III examination which are time consuming. The paper deals with the AT III analysis by means of high performance affinity chromatography (HPAC). The results presented in the paper indicate high sensitivity of HPAC for AT III analysis which can be performed in a few minutes.