THE REGIONAL DIFFERENCE OF NEURONAL SUSCEPTIBILITY IN THE DENTATE GYRUS TO HYPOXIA

被引：14

作者：

HARA, H

ONODERA, H

KOGURE, K

AKAIKE, N

机构：

[1] TOHOKU UNIV,SCH MED,INST BRAIN DIS,DEPT NEUROL,SENDAI,MIYAGI 980,JAPAN

[2] TOHOKU UNIV,SCH MED,DEPT NEUROPHYSIOL,SENDAI,MIYAGI 980,JAPAN

来源：

NEUROSCIENCE LETTERS | 1990年 / 115卷 / 2-3期

关键词：

Dentate gyrus; Guinea pig; Hippocampal slice; Hypoxia; Neuronal susceptibility; Population spike;

D O I：

10.1016/0304-3940(90)90453-G

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of hypoxia on neuronal activity in dentate gyrus granule cells were studied in submerged guinea pig hippocampal slices. In all regions of the dentate gyrus granule, the amplitude of the population spike recorded from the dentate granule cell layers, in response to electrical stimulation of the perforant path, decreased during hypoxia and recovered during reoxygenation. However, the ventral dentate gyrus granule cells (upper blade) were more susceptible to hypoxia than the dorsal ones (lower blade), indicating regional differences of neuronal susceptibility to hypoxia in the dentate gyrus. © 1990.

引用

页码：189 / 194

页数：6

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