CARNITINE IN DRIED BLOOD SPOTS - A METHOD SUITABLE FOR NEONATAL SCREENING

被引：11

作者：

BARNS, RJ ^{[1
]}

BOWLING, FG ^{[1
]}

BROWN, G ^{[1
]}

CLAGUE, AE ^{[1
]}

THOMPSON, A ^{[1
]}

机构：

[1] STATE HLTH LAB SERV,NEONATAL SCREENING UNIT,BRISBANE,AUSTRALIA

来源：

CLINICA CHIMICA ACTA | 1991年 / 197卷 / 01期

关键词：

SUDDEN INFANT DEATH SYNDROME; CARNITINE; MEDIUM CHAIN ACYLCOA DEHYDROGENASE DEFICIENCY; NEONATAL SCREENING;

D O I：

10.1016/0009-8981(91)90345-D

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A method is described which enables the quantitative determination of both free and total carnitine levels in dried blood spots. This method is suitable for neonatal screening for either primary or secondary carnitine deficiency. The 95% confidence interval for free carnitine was 26-76-mu-mol/1 (median = 44) and for total carnitine was 35-102-mu-mol/1 (median = 60).

引用

页码：27 / 34

页数：8

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