COMPONENTS OF OLIGOSACCHARIDES .96. SYNTHESIS OF PARTIAL STRUCTURES OF N-GLYCOPROTEINS OF THE COMPLEX TYPE

被引：66

作者：

PAULSEN, H

HELPAP, B

机构：

来源：

CARBOHYDRATE RESEARCH | 1991年 / 216卷

关键词：

D O I：

10.1016/0008-6215(92)84169-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Comparable syntheses of beta-D-GlcpNAc-(1 --> 2)-[beta-D-GlcpNac--(1 --> 6)]-alpha-D-Manp-(1 --> 6)-beta-D-ManpO(CH2)8CO2Me and beta-D-GlcpNAc-(1 --> 2)-alpha-D-Manp-(1 --> 3)-beta-D-ManpO(CH2)8CO2Me with the glycosyl halide and imidate methods were investigated. 3,4,6-Tri-O-acetyl-2-deoxy-(2,2,2-trichloroethoxycarbonylamino)-alpha-D-glucopyranosyl bromide or trichloroacetimidate are suitable glycosyl donors for beta-D-glycoside coupling with secondary hydroxyl groups.

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页码：289 / 313

页数：25

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