MECHANISTIC STUDIES ON THE PHOSPHORAMIDITE COUPLING REACTION IN OLIGONUCLEOTIDE SYNTHESIS .1. EVIDENCE FOR NUCLEOPHILIC CATALYSIS BY TETRAZOLE AND RATE VARIATIONS WITH THE PHOSPHORUS SUBSTITUENTS

被引：78

作者：

DAHL, BH ^{[1
]}

NIELSEN, J ^{[1
]}

DAHL, O ^{[1
]}

机构：

[1] UNIV COPENHAGEN,HC ORSTED INST,DEPT GEN & ORGAN CHEM,UNIVERSITETSPARKEN 5,DK-2100 COPENHAGEN,DENMARK

来源：

NUCLEIC ACIDS RESEARCH | 1987年 / 15卷 / 04期

关键词：

D O I：

10.1093/nar/15.4.1729

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1729 / 1743

页数：15

共 35 条

[1] HINDERED DIALKYLAMINO NUCLEOSIDE PHOSPHITE REAGENTS IN THE SYNTHESIS OF 2 DNA 51-MERS
ADAMS, SP
KAVKA, KS
WYKES, EJ
HOLDER, SB
GALLUPPI, GR
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (03) : 661 - 663
[2] USE OF 2-PHENYLSULFONYLETHYL AS A PHOSPHATE PROTECTING GROUP IN DNA-SYNTHESIS USING THE PHOSPHITE-TRIESTER APPROACH
BALGOBIN, N
CHATTOPADHYAYA, J
[J]. ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY, 1985, 39 (10): : 883 - 888
[3] BATYEVA ES, 1976, J GEN CHEM USSR, V46, P2120
[4] A SIMPLE AND EFFICIENT PREPARATION OF DEOXYNUCLEOSIDE PHOSPHORAMIDITES INSITU
BEAUCAGE, SL
[J]. TETRAHEDRON LETTERS, 1984, 25 (04) : 375 - 378
[5] DEOXYNUCLEOSIDE PHOSPHORAMIDITES - A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS
BEAUCAGE, SL
CARUTHERS, MH
[J]. TETRAHEDRON LETTERS, 1981, 22 (20) : 1859 - 1862
[6] SOLUTION SYNTHESIS OF PROTECTED DI-2'-DEOXYNUCLEOSIDE PHOSPHOTRIESTERS VIA THE PHOSPHORAMIDITE APPROACH
BEITER, AH
PFLEIDERER, W
[J]. TETRAHEDRON LETTERS, 1984, 25 (19) : 1975 - 1978
[7] BOISDON MT, 1977, TETRAHEDRON LETT, P3501
[8] GENE SYNTHESIS MACHINES - DNA CHEMISTRY AND ITS USES
CARUTHERS, MH
[J]. SCIENCE, 1985, 230 (4723) : 281 - 285
[9] USE OF 2-METHYLSULFONYLETHYL AS A PHOSPHORUS PROTECTING GROUP IN OLIGONUCLEOTIDE SYNTHESIS VIA A PHOSPHITE TRIESTER APPROACH
CLAESEN, C
TESSER, GI
DREEF, CE
MARUGG, JE
VANDERMAREL, GA
VANBOOM, JH
[J]. TETRAHEDRON LETTERS, 1984, 25 (12) : 1307 - 1310
[10] CLAESEN CAA, 1985, RECL TRAV CHIM PAY B, V104, P119

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