CHARACTERIZATION OF THE VARIATION BETWEEN BATCHES OF FAST-FLO LACTOSE USING LOW-FREQUENCY DIELECTRIC-SPECTROSCOPY

被引：8

作者：

CRAIG, DQM ^{[1
]}

DAVIES, CF ^{[1
]}

BOYD, JC ^{[1
]}

HAKES, LB ^{[1
]}

机构：

[1] MERRELL DOW RES INST,WINNERSH RGH 5HQ,BERKS,ENGLAND

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1991年 / 43卷 / 06期

关键词：

D O I：

10.1111/j.2042-7158.1991.tb03508.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The dielectric response of four batches of lactose has been measured over a frequency range of 10(4) to 10(-2) Hz. The spectra corresponding to three of the batches were identical, while the fourth showed a marked reduction in response. This particular batch has also been reported to exhibit longer disintegration times than the other three when formulated as a tablet. The potential use of dielectric spectroscopy as a means of screening batches of pharmaceutical materials is discussed.

引用

页码：444 / 445

页数：2

共 8 条

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