LARGE-SCALE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDE PHOSPHOROTHIOATE USING CONTROLLED-PORE GLASS AS SUPPORT

被引:21
作者
RAVIKUMAR, VT
ANDRADE, M
WYRZYKIEWICZ, TK
SCOZZARI, A
COLE, DL
机构
[1] Isis Pharmaceuticals, Faraday Avenue, Carlsbad
来源
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 06期
关键词
D O I
10.1080/15257779508010685
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An efficient synthesis of oligonucleotide phosphorothioate on a very large-scale using controlled-pore glass as support is described.
引用
收藏
页码:1219 / 1226
页数:8
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