HOW ACCURATE IS SELF-REPORTED FAMILY HISTORY OF COLORECTAL-CANCER

被引:141
作者
AITKEN, J
BAIN, C
WARD, M
SISKIND, V
MACLENNAN, R
机构
[1] UNIV QUEENSLAND,SCH MED,DEPT SOCIAL & PREVENT MED,BRISBANE,QLD,AUSTRALIA
[2] ROYAL BRISBANE HOSP,DEPT GASTROENTEROL,BRISBANE,QLD 4029,AUSTRALIA
基金
英国医学研究理事会;
关键词
BIAS (EPIDEMIOLOGY); COLONIC POLYPS; COLONOSCOPY; COLORECTAL NEOPLASMS; EPIDEMIOLOGIC METHODS; FAMILY CHARACTERISTICS; RECALL;
D O I
10.1093/oxfordjournals.aje.a117522
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Much of the evidence that supports a relation between a positive family history of and increased risk for colorectal cancer is based on information obtained exclusively from patients. There have been few assessments of the accuracy of such data. The validity of self-reported family history of colorectal cancer was assessed in the course of a case-control study of colorectal adenomas conducted among patients aged 20-75 years who underwent colonoscopy in Brisbane, Australia between 1980 and 1985. Family histories reported by a subsample of 237 colonoscopy patients (74 cases and 163 controls) were compared with relatives' medical records and death certificates. Patients' reports of colorectal cancer in 90 relatives were confirmed for 70 (77.8%; 95% confidence interval (CI) 67.8-85.9). Among 124 reports by patients of relatives who had other abdominal cancer or bower conditions, 114 (91.9%; 95% CI 85.7-96.1) were confirmed to be correct, while 10 (8.1%) were found to be colorectal cancer. Finally, 105 (99.1%; 95% CI 94.9-100.0) of a random sample of 106 completely negative reports by patients were confirmed to be correct. Overall, 77% of positive family histories (any positive relatives) were confirmed, and it was estimated that 98% of negative family histories (no positive relatives) were correct. Cases were slightly more accurate than controls in reporting both positive and negative histories among their relatives. By extrapolation of these results to the total sample of 1,244 patients in the larger case-control study, sensitivity of self-reported positive family history was estimated to be 0.87 among cases and 0.82 among controls, and specificity was estimated to be 0.97 in both groups.
引用
收藏
页码:863 / 871
页数:9
相关论文
共 33 条
[1]   CLUES TO THE PATHOGENESIS OF FAMILIAL COLORECTAL-CANCER [J].
AALTONEN, LA ;
PELTOMAKI, P ;
LEACH, FS ;
SISTONEN, P ;
PYLKKANEN, L ;
MECKLIN, JP ;
JARVINEN, H ;
POWELL, SM ;
JEN, J ;
HAMILTON, SR ;
PETERSEN, GM ;
KINZLER, KW ;
VOGELSTEIN, B ;
DELACHAPELLE, A .
SCIENCE, 1993, 260 (5109) :812-816
[2]  
ALSTEAD EM, 1983, GUT, V24, pA998
[3]   ADENOMATOUS POLYPS AND FAMILIAL INCIDENCE OF COLORECTAL-CANCER [J].
ASTE, H ;
SACCOMANNO, S ;
BONELLI, L ;
PUGLIESE, V .
EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1984, 20 (11) :1401-1403
[4]  
BONELLI L, 1988, INT J CANCER, V41, P513
[5]  
Brenner H, 1993, Ann Epidemiol, V3, P289
[6]   COMMON INHERITANCE OF SUSCEPTIBILITY TO COLONIC ADENOMATOUS POLYPS AND ASSOCIATED COLORECTAL CANCERS [J].
CANNONALBRIGHT, LA ;
SKOLNICK, MH ;
BISHOP, T ;
LEE, RG ;
BURT, RW .
NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (09) :533-537
[7]   THE IMPACT OF DIFFERENTIAL RECALL ON THE RESULTS OF CASE-CONTROL STUDIES [J].
DREWS, CD ;
GREELAND, S .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 1990, 19 (04) :1107-1112
[8]  
Fieller EC, 1944, QUART J PHARM PHARMA, V17, P117
[9]  
Floderus B, 1990, Epidemiology, V1, P318, DOI 10.1097/00001648-199007000-00011
[10]   RELATIONSHIP OF DIET TO RISK OF COLORECTAL ADENOMA IN MEN [J].
GIOVANNUCCI, E ;
STAMPFER, MJ ;
COLDITZ, G ;
RIMM, EB ;
WILLETT, WC .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1992, 84 (02) :91-98