UNIQUE 3-BETA-0-METHYLSTEROLS FROM THE PACIFIC SPONGE JEREICOPSIS-GRAPHIDIOPHORA

被引：22

作者：

DAURIA, MV

PALOMA, LG

MINALE, L

RICCIO, R

DEBITUS, C

LEVI, C

机构：

[1] UNIV NAPOLI FEDERICO II,DIPARTIMENTO CHIM SOSTANZE NAT,VIA D MONTESANO 49,I-80131 NAPLES,ITALY

[2] ORSTOM,NOUMEA,NEW CALEDONIA

[3] MUSEUM NATL HIST NAT,BIOL INVERTEBRES MARINS & MALECOL LAB,F-75231 PARIS 05,FRANCE

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 03期

关键词：

D O I：

10.1021/np50081a006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The lipid fraction of the Pacific sponge Jereicopsis graphidiophora has been investigated for its sterol composition. Although the conventional 3-beta-hydroxysteroids were totally absent, the extracts contained unique 3-beta-methoxysteroids. Fifteen 3-beta-methoxysteroids with six different nuclei [DELTA(7,9(11)),DELTA(8,14),DELTA(8),DELTA(7),DELTA(5),5-alpha-saturated] and with five usual C-8-C-10 side chains, have been identified. In addition, the extracts also contained 3-beta-methoxysteroids with oxygenated functionalities in the nuclei: DELTA(7)-9-alpha, 11-alpha-epoxy,DELTA(7)-9-hydroxy,DELTA(8)-7-one,DELTA(8)-14-hydroxy,DELTA(9(11))-8-alpha,14-alpha-epoxy. Characterization was accomplished by gc-ms, hreims, H-1-nmr, C-13-nmr, Ft-ir, and uv spectroscopy.

引用

页码：311 / 320

页数：10

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