APPLICATION OF MICROWAVE-HEATING TO THE SYNTHESIS OF [F-18] FLUOROMISONIDAZOLE

被引：22

作者：

MCCARTHY, TJ ^{[1
]}

DENCE, CS ^{[1
]}

WELCH, MJ ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,EDWARD MALLINCKRODT INST RADIOL,510 S KINGSHIGHWAY BLVD,ST LOUIS,MO 63110

来源：

APPLIED RADIATION AND ISOTOPES | 1993年 / 44卷 / 08期

关键词：

D O I：

10.1016/0969-8043(93)90118-T

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A modified synthesis of [F-18]fluoromisonidazole is reported which makes use of microwave heating to reduce the synthesis time to ca 70 min from EOB. A remote system for column purification, concentration and delivery to an HPLC syringe, which reduces the total absorbed dose to the operator, is also described.

引用

页码：1129 / 1132

页数：4

共 10 条

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