LAMOTRIGINE AS AN ADD-ON DRUG IN THE MANAGEMENT OF LENNOX-GASTAUT SYNDROME

被引：107

作者：

TIMMINGS, PL

RICHENS, A

机构：

[1] Department of Pharmacology and Therapeutics, University of Wales, College of Medicine, Cardiff

来源：

EUROPEAN NEUROLOGY | 1992年 / 32卷 / 06期

关键词：

LAMOTRIGINE; LENNOX-GASTAUT SYNDROME; ANTIEPILEPTIC DRUGS;

D O I：

10.1159/000116849

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report our experience with lamotrigine add-on therapy in the treatment of 11 patients with Lennox-Gastaut syndrome. Lamotrigine is a novel antiepileptic drug, chemically unrelated to the major anticonvulsants in current use. Ten patients experienced a > 50% reduction in seizure frequency, 1 patient experienced no change in seizure frequency. All patients tolerated lamotrigine satisfactorily and no side-effects were reported.

引用

页码：305 / 307

页数：3

共 7 条

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