THE NATIONAL DEPRESSIVE AND MANIC-DEPRESSIVE ASSOCIATION (DMDA) SURVEY OF BIPOLAR MEMBERS

被引:675
作者
LISH, JD
DIMEMEENAN, S
WHYBROW, PC
PRICE, RA
HIRSCHFELD, RMA
机构
[1] UNIV PENN, DEPT PSYCHIAT, AFFECT DISORDERS PROGRAM, PHILADELPHIA, PA 19104 USA
[2] UNIV PENN, DEPT PSYCHIAT, BEHAV GENET PROGRAM, PHILADELPHIA, PA 19104 USA
[3] NATL DEPRESS & MANIC DEPRESS ASSOC, CHICAGO, IL USA
[4] UNIV TEXAS, MED BRANCH, DEPT PSYCHIAT & BEHAV SCI, GALVESTON, TX 77550 USA
关键词
BIPOLAR DISORDER; AGE OF ONSET; COURSE OF ILLNESS; QUALITY OF LIFE; SOCIAL MORBIDITY; TREATMENT;
D O I
10.1016/0165-0327(94)90104-X
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Members of the National Depressive and Manic-Depressive Association who have bipolar disorder were surveyed. 59% of respondents had their first symptoms during childhood or adolescence. Long delays between symptom onset, treatment-seeking, and receipt of a bipolar diagnosis were common. 45% of respondents currently experience frequent recurrences. Child/adolescent onset was associated with a positive family history, depressive or mixed initial symptoms, and frequent recurrence, with predominantly depressive symptoms. Frequent recurrences were associated with depressive or mixed initial symptoms and depressive episodes, but not with medication non-compliance. Both child/adolescent onset and frequent recurrence were associated with increased social morbidity, which was diminished by effective treatment. Respondents with frequent recurrences were less likely to be treated with mood-stabilizers, more likely to be treated with anti-depressants, or anxiolytics, and more likely to report past anxiety symptoms and diagnoses. 13% of respondents had no medical insurance, and 15% had failed to take medicine for financial reasons. The treatment of bipolar illness could be enhanced by (a) public health efforts to promote early diagnosis and treatment; (b) ensuring adequate trials of mood-stabilizers for patients with frequent recurrences; (c) further research on bipolar disorder with prominent anxiety symptoms; and (c) improved access to mental health care.
引用
收藏
页码:281 / 294
页数:14
相关论文
共 56 条
  • [1] WHO RESPONDS TO PROPHYLACTIC LITHIUM
    ABOUSALEH, MT
    COPPEN, A
    [J]. JOURNAL OF AFFECTIVE DISORDERS, 1986, 10 (02) : 115 - 125
  • [2] COURSE OF AFFECTIVE-DISORDERS .2. TYPOLOGY OF BIPOLAR MANIC-DEPRESSIVE ILLNESS
    ANGST, J
    [J]. ARCHIV FUR PSYCHIATRIE UND NERVENKRANKHEITEN, 1978, 226 (01): : 65 - 73
  • [3] COURSE OF AFFECTIVE-DISORDERS .1. CHANGE OF DIAGNOSIS OF MONOPOLAR, UNIPOLAR, AND BIPOLAR ILLNESS
    ANGST, J
    FELDER, W
    FREY, R
    STASSEN, HH
    [J]. ARCHIV FUR PSYCHIATRIE UND NERVENKRANKHEITEN, 1978, 226 (01): : 57 - 64
  • [4] BAASTRUP PC, 1969, ACTA PSYCHIAT SCAND, VS, P12
  • [5] BAUER MS, 1990, ARCH GEN PSYCHIAT, V47, P427
  • [6] BAUER MS, IN PRESS AM J PSYCHI
  • [7] BLACK DW, 1988, ARCH GEN PSYCHIAT, V45, P232
  • [8] CARLSON GA, 1977, AM J PSYCHIAT, V134, P919
  • [9] CHOUINARD G, 1983, BIOL PSYCHIAT, V18, P451
  • [10] DYSPHORIC MANIA
    CLOTHIER, J
    SWANN, AC
    FREEMAN, T
    [J]. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 1992, 12 (01) : S13 - S16