THE CATALYTIC ROLE OF THE ACTIVE-SITE ASPARTIC-ACID IN SERINE PROTEASES

被引：311

作者：

CRAIK, CS

ROCZNIAK, S

LARGMAN, C

RUTTER, WJ

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,HORMONE RES INST,SAN FRANCISCO,CA 94143

来源：

SCIENCE | 1987年 / 237卷 / 4817期

关键词：

D O I：

10.1126/science.3303334

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：909 / 913

页数：5

共 40 条

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[3] STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN .5. ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 A RESOLUTION
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[5] REFINED 2 A X-RAY CRYSTAL-STRUCTURE OF PORCINE PANCREATIC KALLIKREIN-A, A SPECIFIC TRYPSIN-LIKE SERINE PROTEINASE - CRYSTALLIZATION, STRUCTURE DETERMINATION, CRYSTALLOGRAPHIC REFINEMENT, STRUCTURE AND ITS COMPARISON WITH BOVINE TRYPSIN
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[J]. JOURNAL OF MOLECULAR BIOLOGY, 1983, 164 (02) : 237 - 282
[6] MOLECULAR-STRUCTURE OF THE ALPHA-LYTIC PROTEASE FROM MYXOBACTER-495 AT 2-8-A RESOLUTION
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[J]. JOURNAL OF MOLECULAR BIOLOGY, 1979, 131 (04) : 743 - 775
[7] MOLECULAR-STRUCTURE OF CRYSTALLINE STREPTOMYCES-GRISEUS PROTEASE-A AT 2.8-A RESOLUTION .2. MOLECULAR-CONFORMATION, COMPARISON WITH ALPHA-CHYMOTRYPSIN AND ACTIVE-SITE GEOMETRY
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[J]. JOURNAL OF MOLECULAR BIOLOGY, 1978, 124 (01) : 261 - 283
[8] 4.5 A RESOLUTION STRUCTURE OF A BACTERIAL SERINE PROTEASE FROM STREPTOMYCES-GRISEUS
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[J]. CANADIAN JOURNAL OF BIOCHEMISTRY, 1974, 52 (03): : 208 - 220
[9] REDESIGNING TRYPSIN - ALTERATION OF SUBSTRATE-SPECIFICITY
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LARGMAN, C
FLETCHER, T
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RUTTER, WJ
[J]. SCIENCE, 1985, 228 (4697) : 291 - 297
[10] CRAIK CS, UNPUB

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