ELECTROCHEMICAL DETECTOR WITH A DROPPING MERCURY-ELECTRODE FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

The electrochemical flow-through cell described has an active volume of less than 1 μl, and incorporates a dropping mercury electrode with drop times of about 0.05 s. Its performance as a detector for high-performance liquid chromatography is assessed for p-nitrophenol and nitrobenzene. The detection limits are 4-5 ng; the relative standard deviation of the peak height is better than 5% for the range 5-150 ng. The dependence of the response on flow rate, mercury pressure and drop time is described. © 1979.