ANTIBODIES TO HEPATITIS-C VIRUS IN BLOOD-DONORS

被引：7

作者：

FERRONI, P

TAGGER, A

RIBERO, ML

GROSSI, A

PREGLIASCO, F

PASQUALI, ML

SALVANESCHI, S

机构：

[1] Istituto di Virologia, Università di Milano, Milano, 20123, Via C. Pascal

[2] Istituto di Igiene, Universita di Milano

[3] Servizio di Immunoematologia, Istituto Nazionale dei Tumori, Milano

[4] Centro Trasfusionale A. V.I.S., Pavia

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1990年 / 6卷 / 03期

关键词：

Antibody; Blood donors; Hepatitis B virus; Hepatitis C virus;

D O I：

10.1007/BF00150442

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Recently a recombinant polypeptide of hepatitis C virus (HCV) has been developed by the Chiron Corporation in California. This antigen has been used to develop an ELISA test (Ortho Diagnostic Systems) for serum anti-HCV antibodies. Preliminary data have shown that this virus is the major cause of NANB hepatitis in the world. We examined differences in anti-HCV prevalence among subgroups of blood donors (total sera examined 639) classified for past or present exposure to HBV or not, and for ALT levels. The anti-HCV prevalence found in regular blood donors with normal ALT levels and no antibody to HBcAg was 1.2%. No significant difference in the anti-HCV prevalence was found among other subgroups of blood donors except that a higher prevalence (10%) was found in a group with both elevated ALT and HBV markers. These preliminary findings suggest that the policy of blood supply should take into account the advent of HCV antibody test. © 1990 Kluwer Academic Publishers.

引用

页码：326 / 328

页数：3

共 5 条

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[2]

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[4]

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