THE HUMAN GLUTATHIONE-PEROXIDASE GENES GPX2, GPX3, AND GPX4 MAP TO CHROMOSOME-14, CHROMOSOME-5, AND CHROMOSOME-19, RESPECTIVELY

被引：74

作者：

CHU, FF

机构：

[1] Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 66卷 / 02期

关键词：

D O I：

10.1159/000133675

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

cDNA probes of human glutathione peroxidase (GSHPx) genes, including the classic GPX1 (GSHPx-1), the newly characterized GPX2 (GSHPx-GI), the plasma enzyme GPX3 (GSHPx-P), and the phospholipid hydroperoxide glutathione peroxidase GPX4 (PHGPX), were hybridized to Southern blots containing genomic DNA from human x hamster somatic cell hybrids. GPXZ was mapped to chromosome 14, GPX3 to chromosome 5 and GPX4 to chromosome 19. Additionally, human chromosomes 3 and 21 and the X chromosome were shown to contain sequences homologous to GPX1, as reported previously.

引用

页码：96 / 98

页数：3

共 11 条

[1]

ISOLATION AND CHROMOSOMAL LOCALIZATION OF THE HUMAN GLUTATHIONE-PEROXIDASE GENE [J].