A STEREOSPECIFIC SYNTHESIS OF 2',3'-DIDEOXY-BETA-L-CYTIDINE (BETA-L-DDC), A POTENT INHIBITOR AGAINST HUMAN HEPATITIS-B VIRUS (HBV) AND HUMAN-IMMUNODEFICIENCY-VIRUS (HIV)

被引：26

作者：

LIN, TS ^{[1
]}

LUO, MZ ^{[1
]}

LIU, MC ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,CTR COMPREHENS CANC,NEW HAVEN,CT 06520

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)73214-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2',3'-Dideoxy-beta-L-cytidine (beta-L-ddC), a potent inhibitor against human hepatitis B virus (HBV) and human immunodeficiency virus (HIV), has been stereospecifically synthesized from L-arabinose in 9 steps.

引用

页码：3477 / 3480

页数：4

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