SINGLE T-CELL PROBES FOR ANTIGEN MHC EXPRESSION

被引：8

作者：

SHASTRI, N

机构：

[1] Division of Immunology, Department of Molecular and Cell Biology, University of California, Berkeley

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0952-7915(95)80012-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of party events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.

引用

收藏

页码：258 / 262

页数：5

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