METALATION REACTIONS .16. POLYLITHIATION OF 1,3,5-TRIMETHOXYBENZENE AND 1,2,4-TRIMETHOXYBENZENE

被引：11

作者：

CABIDDU, S

CONTINI, L

FATTUONI, C

FLORIS, C

GELLI, G

机构：

[1] Dipartimento di Scienze Chimiche, Università, I-09124 Cagliari, Via Ospedale

来源：

TETRAHEDRON | 1991年 / 47卷 / 44期

关键词：

D O I：

10.1016/S0040-4020(01)96216-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Polylithiation reactions of 1,3,5- and 1,2,4-trimethoxybenzenes have been investigated. Results showed that it is possible to substitute all arylic hydrogens through one-pot sequential bimetalation/monometalation, monometalation/bimetalation or three monometalations. This reaction is strongly affected by steric hindrance.

引用

收藏

页码：9279 / 9288

页数：10

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