ISOLATION AND IDENTIFICATION OF S(+)-3-HYDROXYISOBUTYRIC ACID IN THE URINE OF RATS LOADED WITH ISOBUTYRIC ACID

被引：5

作者：

AMSTER, J

TANAKA, K

机构：

[1] Department of Human Genetics, Yale University School of Medicine, New Haven, CT

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 585卷 / 04期

关键词：

(Rat urinary metabolism); Isobutyrate dehydrogenation; S(+)-3-Hydroxyisobutyric acid; Stereoisomerism;

D O I：

10.1016/0304-4165(79)90196-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

3-Hydroxyisobutyric acid has been isolated from the urine of rats loaded with sodium isobutyrate. An optical rotation measurement of the methyl ester derivative shows this compound to be the S(+) stereoisomer. This is the same stereoisomer that has been previously identified in cultures of bacteria incubated with ammonium isobutyrate. © 1979.

引用

页码：643 / 644

页数：2