LITHIUM AUGMENTATION IN SERTRALINE-RESISTANT DEPRESSION - A PRELIMINARY DOSE-RESPONSE STUDY

被引：42

作者：

DINAN, TG

机构：

[1] Department of Psychological Medicine, St Bartholomew's Hospital, London

来源：

ACTA PSYCHIATRICA SCANDINAVICA | 1993年 / 88卷 / 04期

关键词：

SERTRALINE; LITHIUM; DEPRESSION; TREATMENT RESISTANCE;

D O I：

10.1111/j.1600-0447.1993.tb03461.x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Eleven patients with DSM-III-R major depression who were treatment-resistant to sertraline were allocated for lithium augmentation therapy. In conjunction with their sertraline, 6 received lithium carbonate 400 mg at night and 5 received 800 mg at night. A total of 7 patients responded within 1 week. The degree of response was not related to the serum lithium level. Patients with lithium levels as low as 0.3 mEq/l responded. No significant side effects were reported.

引用

页码：300 / 301

页数：2

共 13 条

[1]

American Psychiatric Association, 1987, DIAGNOSTIC STAT MANU, V3rd

[2] LITHIUM INDUCES RAPID RELIEF OF DEPRESSION IN TRICYCLIC ANTI-DEPRESSANT DRUG NON-RESPONDERS [J].