ANTIBODY-RESPONSE IN 4 ANIMAL SPECIES TO 2 DIFFERENT INFLUENZA A-SWINE VIRUSES

被引：2

作者：

DOLEZALOVA, B ^{[1
]}

ZAVADOVA, H ^{[1
]}

STAREK, M ^{[1
]}

VONKA, V ^{[1
]}

机构：

[1] INST SERA & VACCINES,DEPT EXPTL VIROL,PRAGUE 10,CZECHOSLOVAKIA

来源：

JOURNAL OF BIOLOGICAL STANDARDIZATION | 1978年 / 6卷 / 03期

关键词：

D O I：

10.1016/S0092-1157(78)80001-8

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Hamsters were infected with the A/Swine/Ann Arbor/31 virus or the X-53 recombinant possessing the haemagglutinin and neuraminidase of A/Swine/New Jersey/76 virus. In a series of other tests, hamsters, mice, rabbits and guinea-pigs were inoculated with formalin-inactivated Ann Arbor virus and revaccinated either with inactivated Ann Arbor or with X-53 virus. The animal sera were tested for haemagglutination-inhibiting antibody; in hamsters, also the formation of neuraminidase-inhibiting antibodies was investigated. The results revealed a close antigenic relationship between both of the surface antigens of the two viruses. Because of the excellent growth of Ann Arbor in chick embryos, it is suggested that the X-53 virus could be substituted by the Ann Arbor virus in influenza A/Swine vaccine production. © 1978 The International Association of Biological Standardization.

引用

页码：165 / 171

页数：7