IMIDAZOLE ACETIC-ACID AS A SUBSTITUTE FOR CAMP

被引：16

作者：

KLINE, EL ^{[1
]}

BANKAITIS, V ^{[1
]}

BROWN, CS ^{[1
]}

MONTEFIORI, D ^{[1
]}

机构：

[1] CLEMSON UNIV,DEPT BIOCHEM,CLEMSON,SC 29631

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)91832-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability of imidazole acetic acid (IA) to substitute for cAMP was demonstrated by use of a series of strains carrying a lesion in the cya structural gene. The substitution of IA for cAMP was specific for the L-arabinose operon in that this compound was ineffective in substituting for cAMP in the lactose or maltose catabolic systems. The cAMP receptor protein (CRP) and the araC gene product were necessary for the IA mediated induction of the L-arabinose system. © 1979.

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页码：566 / 574

页数：9

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