STEREOSELECTIVE DISPOSITION OF FLECAINIDE IN RELATION TO THE SPARTEINE DEBRISOQUINE METABOLIZER PHENOTYPE

被引：40

作者：

GROSS, AS

MIKUS, G

FISCHER, C

HERTRAMPF, R

GUNDERTREMY, U

EICHELBAUM, M

机构：

[1] DR MARGARETE FISCHER BOSCH INST CLIN PHARMACOL,AUERBACHSTR 112,D-7000 STUTTGART 50,FED REP GER

[2] BUNDESGESUNDHEITSAMT,INST ARZNEIMITTEL,D-1000 BERLIN 40,FED REP GER

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1989年 / 28卷 / 05期

关键词：

D O I：

10.1111/j.1365-2125.1989.tb03542.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：555 / 566

页数：12

共 29 条

[1] RESOLUTION OF FLECAINIDE ACETATE, N-(2-PIPERIDYLMETHYL)-2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZAMIDE ACETATE, AND ANTIARRHYTHMIC PROPERTIES OF THE ENANTIOMERS
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[5] FLECAINIDE HALF-LIFE PROLONGATION IN 2 PATIENTS WITH CONGESTIVE HEART-FAILURE AND COMPLEX VENTRICULAR ARRHYTHMIAS
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[6] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE QUANTITATION OF A META-O-DEALKYLATED METABOLITE OF FLECAINIDE ACETATE, A NEW ANTIARRHYTHMIC
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[J]. JOURNAL OF CHROMATOGRAPHY, 1985, 343 (01): : 119 - 127
[7] METABOLISM OF FLECAINIDE
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[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1984, 53 (05) : B41 - B51
[8] DRAYER DE, 1988, DRUG STEREOCHEMISTRY
[9] ENANTIOSELECTIVITY OF 4-HYDROXYLATION IN EXTENSIVE AND POOR METABOLIZERS OF DEBRISOQUINE
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[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1988, 25 (04) : 505 - 508
[10] PHARMACOKINETIC AND PHARMACODYNAMIC CONSEQUENCES OF STEREOSELECTIVE DRUG-METABOLISM IN MAN
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[J]. BIOCHEMICAL PHARMACOLOGY, 1988, 37 (01) : 93 - 96

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