MM-46115, A NEW ANTIVIRAL ANTIBIOTIC FROM ACTINOMADURA-PELLETIERI - CHARACTERISTICS OF THE PRODUCING CULTURES, FERMENTATION, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

被引：20

作者：

ASHTON, RJ ^{[1
]}

KENIG, MD ^{[1
]}

LUK, K ^{[1
]}

PLANTEROSE, DN ^{[1
]}

SCOTTWOOD, G ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,GREAT BURGH,YEW TREE BOTTOM RD,EPSOM KT18 5XQ,SURREY,ENGLAND

来源：

JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 11期

关键词：

D O I：

10.7164/antibiotics.43.1387

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Six strains of Actinomadura pelletieri were shown to produce a novel macrolide antibiotic, designated MM 46115. MM 46115 was active against parainfluenza virus 1 and 2 and Grampositive bacteria. Methods are described for the production of MM 46115 by strain IP 729.63, and for the isolation of the compound from a butanol extract of the culture filtrate.

引用

页码：1387 / 1393

页数：7

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