OXIDATIVE DESULFURIZATION-FLUORINATION OF METHYL ARENEDITHIOCARBOXYLATES - A CONVENIENT SYNTHESIS OF TRIFLUOROMETHYLATED AROMATIC-COMPOUNDS

被引：33

作者：

KUROBOSHI, M ^{[1
]}

HIYAMA, T ^{[1
]}

机构：

[1] SAGAMI CHEM RES CTR, 4-4-1 NISHIOHNUMA, SAGAMIHARA, KANAGAWA 229, JAPAN

来源：

CHEMISTRY LETTERS | 1992年 / 05期

关键词：

D O I：

10.1246/cl.1992.827

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Trifluoromethyl-substituted aromatic compounds were obtained by oxidative desulfurization-fluorination reaction of methyl arenedithiocarboxylates using n-Bu4N+H2F3- and 1,3-dibromo-5,5-dimethylhydantoin (DBH). Use of N-bromosuccinimide or N-iodosuccinimide instead of DBH afforded difluoro(methylthio)methyl-substituted aromatics.

引用

页码：827 / 830

页数：4

共 21 条

[1] Preparation of m-fluorobenzotrifluoride [J].

Aelony, D .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1934, 56 (07) :2063-2063

[2]

ALBERT P, 1986, B SOC CHIM FR, P910

[3]

BECKE F, 1969, CHEM ZTG, V93, P474

[4]

Boswell G. A., 1974, ORG REACTIONS, V21, P1

[5]

FALBE J, 1985, METHODEN ORGANISCH E, V5, P891

[6]

Filler R., 1982, BIOMEDICAL ASPECTS F

[7] THE CHEMISTRY OF SULFUR TETRAFLUORIDE .2. THE FLUORINATION OF ORGANIC CARBONYL COMPOUNDS [J].

HASEK, WR ;

SMITH, WC ;

ENGELHARDT, VA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1960, 82 (03) :543-551

[8]

KOBAYASHI Y, 1978, CHEM PHARM BULL, V26, P1247

[9] REACTIONS OF AROMATIC TRIFLUOROMETHYL COMPOUNDS WITH NUCLEOPHILIC-REAGENTS [J].

KOBAYASHI, Y ;

KUMADAKI, I .

ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (05) :197-204

[10]

KOBAYASHI Y, 1969, TETRAHEDRON LETT, P4095

← 1 2 3 →