A QUANTITATIVE TEST OF LONG-RANGE CORRELATIONS AND COMPOSITIONAL FLUCTUATIONS IN DNA-SEQUENCES

被引：11

作者：

CHATZIDIMITRIOUDREISMANN, CA ^{[1
]}

STREFFER, RMF ^{[1
]}

LARHAMMAR, D ^{[1
]}

机构：

[1] UPPSALA UNIV,DEPT MED GENET,UPPSALA,SWEDEN

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1994年 / 224卷 / 02期

关键词：

D O I：

10.1111/j.1432-1033.1994.00365.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent findings concerning long-range correlations and fractals in intron-containing DNA sequences of living organisms are tested qualitatively and quantitatively. Extending previous studies, we demonstrate that these findings are trivially equivalent to variations of the base-pair composition in different regions of a DNA sequence. It is shown explicitly that a well-defined scaling or fractal exponent does not exist anywhere. Comparisons of natural DNAs with computer-generated, artificial sequences are made. The present study reveals that certain natural DNA sequences (especially those with compact genomes) do have stochastic characteristics which are intrinsically different from artificial sequences. The results for 21 DNA sequences of various types from widely different taxa are reported.

引用

页码：365 / 371

页数：7

共 16 条

[1] MATHEMATICAL BIOLOGY - DNA SHOWS UNEXPLAINED PATTERNS WRIT LARGE [J].