(R)-O-ARYLLACTIC ACIDS - CONVENIENT CHIRAL SOLVATING AGENTS FOR DIRECT H-1-NMR DETERMINATION OF THE ENANTIOMERIC COMPOSITION OF AMINES AND AMINO-ALCOHOLS

被引：20

作者：

CHINCHILLA, R ^{[1
]}

FOUBELO, F ^{[1
]}

NAJERA, C ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03080 ALACANT,SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 08期

关键词：

D O I：

10.1016/0957-4166(95)00241-G

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(R)-O-(4-Chloro-2-methylphenyl)- and (R)-O-(2-naphthyl)lactic acids are very efficent chiral solvating agents for the direct H-1 NMR assay of the enantiomeric composition especially for primary and secondary amines and significant amino alcohols such as propranalol and fluoxetine.

引用

页码：1877 / 1880

页数：4

共 15 条

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[7] THE CONFORMATION OF DERIVATIVES OF O-ARYLLACTIC ACID USED AS CHIRAL REAGENTS IN STRUCTURE DETERMINATION - NMR AND X-RAY STRUCTURE-ANALYSIS OF DIASTEREOISOMERIC MENTHOL ESTERS
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[10] KINETIC RESOLUTION OF RACEMIC CARBOXYLIC-ACIDS AND ALCOHOLS WITH HOMOCHIRAL ALCOHOLS AND CARBOXYLIC-ACIDS, RESPECTIVELY, AND THE MUKAIYAMA OR PALOMO REAGENTS
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