APPEARANCE OF CYTOPLASMIC DNA POLYMERASE ACTIVITY DURING MATURATION OF AMPHIBIAN OOCYTES INTO EGGS

被引:44
作者
GURDON, JB
SPEIGHT, VA
机构
[1] Department of Zoology, Oxford, Parks Road
基金
英国医学研究理事会;
关键词
D O I
10.1016/0014-4827(69)90488-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Previous work has shown that purified DNA serves as a template for replication when injected into frogs' eggs. The experiments reported here demonstrate that purified DNA is not replicated when injected into the cytoplasm of oocytes. The results indicate that cytoplasmic DNA polymerase activity appears when oocytes are converted into eggs during the completion of meiosis and that this may be partly responsible for the induction of nuclear DNA synthesis which follows fertilization. © 1969.
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页码:253 / &
相关论文
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BRACHET J., 1967, COMPR BIOCHEM, V28, P23
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CAMPBELL PN, 1968, ESSAYS BIOCHEMIST ED, V4, P26
[3]   CYTOPLASMIC CONTROL OF NUCLEAR ACTIVITY IN ANIMAL DEVELOPMENT [J].
GURDON, JB ;
WOODLAND, HR .
BIOLOGICAL REVIEWS, 1968, 43 (02) :233-+
[5]  
GURDON JB, IN PRESS
[6]  
GURDON JB, 1968, ESSAYS BIOCHEM, V4, P26
[7]  
WOODLAND HR, IN PRESS