LABILE TESTOSTERONE CONJUGATE IN HUMAN-URINE - FURTHER EVIDENCE

被引:3
作者
KJELD, JM [1 ]
PUAH, CM [1 ]
JOPLIN, GF [1 ]
机构
[1] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,ENDOCRINE UNIT,LONDON W12 0HS,ENGLAND
关键词
D O I
10.1016/0009-8981(79)90093-7
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
The origin of unconjugated testosterone released in human urine on storage and by dilute sulphuric acid treatment has been studied further. Various extraction procedures of urine have been employed and a new methodology involving anion exchange followed by acid hydrolysis and radioimmunoassay of the released unconjugated testosterone. Results indicate that human urine contains a very labile conjugate of testosterone and 5α-dihydrotestosterone with polar solubility properties and a negative charge. © 1979.
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页码:227 / 233
页数:7
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