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POLYS LAMENT - THE NEGLECTED ROLE OF THE POLYMORPHONUCLEAR NEUTROPHIL IN THE AFFERENT LIMB OF THE IMMUNE-RESPONSE

被引：403
作者：
LLOYD, AR
OPPENHEIM, JJ
机构：
[1] Laboratory of Molecular Immunoregulation, National Cancer Institute, Frederick
来源：
IMMUNOLOGY TODAY | 1992年 / 13卷 / 05期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/0167-5699(92)90121-M
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The polymorphonuclear leucocyte (PMN) has traditionally been thought to participate in the inflammatory response only as an effector cell. However, recent data demonstrate that PMNs can synthesize and release cytokines, such as IL-1, TNF-alpha and IL-6, and hence modulate both T- and B-cell activities in the evolution of an immune response.
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页码：169 / 172
页数：4
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