SOMATOSTATIN RECEPTOR IMAGING IN NONFUNCTIONING PITUITARY-ADENOMAS - VALUE OF AN UPTAKE INDEX

被引：23

作者：

DUET, M

MUNDLER, O

AJZENBERG, C

BEROLATTI, B

CHEDIN, P

DURANTEAU, L

WARNET, A

机构：

[1] HOP LARIBOISIERE,DEPT NUCL MED,F-75475 PARIS,FRANCE

[2] HOP LARIBOISIERE,DEPT INTERNAL MED,F-75475 PARIS,FRANCE

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE | 1994年 / 21卷 / 07期

关键词：

SOMATOSTATIN RECEPTOR IMAGING; PITUITARY SCINTIGRAPHY; NONFUNCTIONING ADENOMAS; SOMATOSTATIN ANALOGS; IN-111; PENTETREOTIDE;

D O I：

10.1007/BF00285587

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Somatostatin receptor imaging (SRI) was performed in five patients with known non-functioning pituitary adenomas. To determine whether the pituitary uptake correlates with response to octreotide therapy, an uptake index (UI) was calculated. Pituitary adenomas were detected in all five patients. The UI was, respectively, 15.1, 3.7, 2.2, 2.2 and 2.2 (the UI calculated in 12 normal subjects was between 1 and 1.9). Only the patient with the highest UI (15.1) had a dramatic improvement in tumour volume and visual function in response to octreotide therapy. The UI might be a good predictive parameter of octreotide therapy efficacy in non-functioning adenomas.

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收藏

页码：647 / 650

页数：4

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