ABILITY OF GLUCAGON TO PRODUCE CARDIAC STIMULATION WITHOUT ARRHYTHMIAS IN HALOTHANE-ANAESTHETIZED ANIMALS

被引：22

作者：

KATZ, RL

HINDS, L

MILLS, CJ

机构：

[1] Department of Anesthesiology, Columbia University, College of Physicians and Surgeons, New York

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1969年 / 41卷 / 07期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/bja/41.7.574

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Summary: The cardiovascular effects of glucagon were determined in cats and dogs anaesthetized with halothane. Glucagon increased heart rate and myocardial contractility but did not produce ventricular arrhythmias. Adrenaline and isoprenaline, which also increased heart rate and myocardial contractility, did produce ventricular arrhythmias. The cardiac stimulant effects of glucagon were not prevented by beta-adrenergic blockade while those of adrenaline and isoprenaline were. © 1969 John Sherratt and Son Ltd.

引用

页码：574 / &

共 25 条

[1]

CATENACCI AJ, 1963, JAMA-J AM MED ASSOC, V183, P662

[2]

FARAH A, 1960, J PHARMACOL EXP THER, V129, P49

[3]

FLEMING WW, 1962, P SOC EXP BIOL MED, V111, P484

[4] GLUCAGON - ITS ENHANCEMENT OF CARDIAC PERFORMANCE IN CAT AND DOG AND PERSISTENCE OF ITS INOTROPIC ACTION DESPITE BETA-RECEPTOR BLOCKADE WITH PROPRANOLOL [J].