STEROIDS FROM AQUATIC ORGANISMS .19. NEW STEROLS FROM THE ANTARCTIC SPONGE ARTEMISINA-APOLLINIS

The steroidal composition of the sponge Artemisina apollinis from the Antarctic Ocean was studied by GC-MS and 1H NMR. The sponge contains twenty-eight C25-C30 derivatives having four different types of nucleus: 3β-hydroxy-5 α H-, 3-keto-5 α H-derivatives, 3β-hydroxy-Δ5- and 3β-hydroxy-Δ7-derivatives. Compounds with the first two nucleus are the most abundant, with similar side chain patterns and identical GC profiles. The 3-keto-5 α H-derivatives constitute a new group of natural products. © 1990, Walter de Gruyter. All rights reserved.