This study explores the explanatory models of major depression in a group of 40 recently immigrated Chinese-American women, and demonstrates the significant relationship between problem conceptualization and help-seeking behavior. Respondents are presented a vignette depicting major depression, from which they are asked to conceptualize the problem described and answer questions regarding its cause, impact and potential sources for help-seeking. Those who provide a psychological conceptualization are likely not to suggest professional services, but to turn to themselves and family and friends for assistance. On the other hand, those who hold a physical conceptualization are likely to seek out medical services. Implications for effective mental health service delivery to this population are discussed. © 1990 Kluwer Academic Publishers.