THE EFFECT OF SYSTEMICALLY AND LOCALLY ADMINISTERED STEROIDS ON VIP-LIKE IMMUNOREACTIVE CELLS IN THE PARAVENTRICULAR NUCLEUS OF ADRENALECTOMIZED RATS

被引：10

作者：

BARTHA, L

KIEM, DT

MAKARA, GB

机构：

[1] Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest

来源：

BRAIN RESEARCH | 1990年 / 506卷 / 02期

关键词：

Dexamethasone; Immunocytochemistry; Sex steroid; Vasoactive intestinal peptide;

D O I：

10.1016/0006-8993(90)91272-I

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Seven days after adrenalectomy (ADX) the number of vasoactive intestinal peptide (VIP)- and corticotropin-releasing factor (CRF)-immunoreactive cells in the parvocellular part of the rat paraventricular nucleus (PVN) increased markedly. Dexamethasone in the drinking water (started immediately after ADX) or its local implantation around the hypothalamic PVN reduced the ADX-induced increase in the number of VIP- and CRF-like immunoreactive neurons. The present results suggest that PVN might be the site at which glucocorticoids inhibit the increase in VIP-positive cells after ADX. © 1990.

引用

收藏

页码：323 / 326

页数：4

相关论文

共 14 条

[1] VASOACTIVE INTESTINAL POLYPEPTIDE IS SYNTHESIZED IN ANTERIOR-PITUITARY TISSUE [J].

ARNAOUT, MA ;

GARTHWAITE, TL ;

MARTINSON, DR ;

HAGEN, TC .

ENDOCRINOLOGY, 1986, 119 (05) :2052-2057

[2] VASOACTIVE INTESTINAL PEPTIDE (VIP) - BRAIN DISTRIBUTION, SUBCELLULAR-LOCALIZATION AND EFFECT OF DEAFFERENTATION OF THE HYPOTHALAMUS IN MALE-RATS [J].

BESSON, J ;

ROTSZTEJN, W ;

LABURTHE, M ;

EPELBAUM, J ;

BEAUDET, A ;

KORDON, C ;

ROSSELIN, G .

BRAIN RESEARCH, 1979, 165 (01) :79-85

[3]

CECATELLI S, 1988, NEUROSCI LETT, V84, P29

[4] LACTATION ELEVATES VASOACTIVE INTESTINAL PEPTIDE MESSENGER RIBONUCLEIC-ACID IN RAT SUPRACHIASMATIC NUCLEUS [J].

GOZES, I ;

AVIDOR, R ;

BIEGON, A ;

BALDINO, F .

ENDOCRINOLOGY, 1989, 124 (01) :181-186

[5] ANALYSIS OF PEPTIDE HISTIDINE-ISOLEUCINE VASOACTIVE INTESTINAL POLYPEPTIDE-IMMUNOREACTIVE NEURONS IN THE CENTRAL NERVOUS-SYSTEM WITH SPECIAL REFERENCE TO THEIR RELATION TO CORTICOTROPIN RELEASING FACTOR-LIKE AND ENKEPHALIN-LIKE IMMUNOREACTIVITIES IN THE PARAVENTRICULAR HYPOTHALAMIC NUCLEUSS [J].

HOKFELT, T ;

FAHRENKRUG, J ;

JU, G ;

CECCATELLI, S ;

TSURUO, Y ;

MEISTER, B ;

MUTT, V ;

RUNDGREN, M ;

BRODIN, E ;

TERENIUS, L ;

HULTING, AL ;

WERNER, S ;

BJORKLUND, H ;

VALE, W .

NEUROSCIENCE, 1987, 23 (03) :827-857

[6] GLUCOCORTICOID IMPLANTS AROUND THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS PREVENT THE INCREASE OF CORTICOTROPIN-RELEASING FACTOR AND ARGININE VASOPRESSIN IMMUNOSTAINING INDUCED BY ADRENALECTOMY [J].

KOVACS, K ;

KISS, JZ ;

MAKARA, GB .

NEUROENDOCRINOLOGY, 1986, 44 (02) :229-234

[7] INTERACTION OF VASOACTIVE INTESTINAL PEPTIDE (VIP) AND GROWTH-HORMONE RELEASING-FACTOR (GRF) WITH CORTICOTROPIN RELEASING-FACTOR (CRF) ON CORTICOTROPIN SECRETION INVITRO [J].

LEONARD, JF ;

BLUETPAJOT, MT ;

OLIVER, C ;

KORDON, C .

NEUROPEPTIDES, 1988, 12 (03) :131-133

[8] VASOACTIVE INTESTINAL PEPTIDE-CONTAINING NEURONS IN THE PARAVENTRICULAR NUCLEUS MAY PARTICIPATE IN REGULATING PROLACTIN SECRETION [J].

MEZEY, E ;

KISS, JZ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (01) :245-247

[9]

Paxinos G., 2007, RAT BRAIN STEROTAXIC

[10] EFFECT OF STEROIDS ON VASOACTIVE INTESTINAL PEPTIDE IN DISCRETE BRAIN-REGIONS AND PERIPHERAL-TISSUES [J].

ROTSZTEJN, WH ;

BESSON, J ;

BRIAUD, B ;

GAGNANT, L ;

ROSSELIN, G ;

KORDON, C .

NEUROENDOCRINOLOGY, 1980, 31 (04) :287-291