NUCLEOTIDE-SEQUENCE OF THE HERPES-SIMPLEX VIRUS TYPE-2 SYN GENE THAT CAUSES CELL-FUSION

被引:10
作者
DEBROY, C [1 ]
机构
[1] PENN STATE UNIV, DEPT MOLEC & CELL BIOL, UNIVERSITY PK, PA 16802 USA
关键词
Cloning; comparison with HSV-1; predicted amino acid sequence;
D O I
10.1016/0378-1119(90)90043-Q
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The nucleotide (nt) sequence of the entire coding reion of the syn gene of Herpes simplex virus type 2 (HSV-2) is reported. The amino acid (aa) sequence deduced from the nt sequence has been compared to analogous Herpes simplex virus type 1 (HSV-1) syn gene that causes cell fusion. The aa sequences are 82.8% homologous and contain a highly conserved region of 90 aa. These results identify some of the conserved regions in the coding sequences between the two types. © 1990.
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页码:275 / 277
页数:3
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