ASYMMETRIC-SYNTHESIS OF CHIRAL FLUORINATED COMPOUNDS

被引：17

作者：

ISEKI, K

KOBAYASHI, Y

机构：

[1] MEC Laboratory, Daikin Industries Ltd.

来源：

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 1994年 / 52卷 / 01期

关键词：

CHIRAL FLUORINATED COMPOUNDS; ASYMMETRIC SYNTHESIS; MONOFLUORINATION; FLUOROALKYLATION; TRIFLUOROMETHYLATION;

D O I：

10.5059/yukigoseikyokaishi.52.40

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of chiral compounds having fluorine atoms has become an important part of organofluorine chemistry in connection with analytical, biological and medicinal chemistry and opto-electric substances such as liquid crystals. This review is focused on asymmetric synthesis of chiral compounds having a fluorine atom or a fluoroalkyl group (especially a trifluoromethyl group). The examples cited in this review are divided in three different types; (a) asymmetric monofluorination, (b) asymmetric fluoroalkylation (trifluoromethylation), and (c) conversion from prochiral fluorinated compounds.

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页码：40 / 48

页数：9

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