ORIGIN OF BISTRAMIDE A IDENTIFIED IN LISSOCLINUM-BISTRATUM (UROCHORDATA) - POSSIBLE INVOLVEMENT OF SYMBIOTIC PROCHLOROPHYTA

被引:11
作者
BIARD, JF [1 ]
GRIVOIS, C [1 ]
VERBIST, JF [1 ]
DEBITUS, C [1 ]
CARRE, JB [1 ]
机构
[1] ORSTOM,NOUMEA,NEW CALEDONIA
关键词
D O I
10.1017/S0025315400059014
中图分类号
Q17 [水生生物学];
学科分类号
071004 ;
摘要
An attempt was made to determine whether bistramide A (=bistratene A), a polycycloether with biological activity isolated homLissoclinum bistratum Sluiter, originates from the ascidian itself or from its symbiont Prochlorophyta. A high-pressure liquid chromatography assay carried out on the whole ascidian, the ascidian without a portion of its Prochloron and the Prochloron themselves gave concentrations respectively of 0.182, 0.166 and 0.850%. In view of these results, as well as of the capacity of Prochloron to synthesize complex nitrogenous products and the cytotoxicity of these products, it is hypothesized that bistramide A originates exclusively in Prochloron. © 1990, Marine Biological Association of the United Kingdom. All rights reserved.
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页码:741 / 746
页数:6
相关论文
共 14 条
[1]   NOVEL CYTO-TOXIC COMPOUNDS FROM THE ASCIDIAN LISSOCLINUM-BISTRATUM [J].
DEGNAN, BM ;
HAWKINS, CJ ;
LAVIN, MF ;
MCCAFFREY, EJ ;
PARRY, DL ;
WATTERS, DJ .
JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (06) :1354-1359
[2]   PROTON NUCLEAR MAGNETIC STUDY OF BISTRAMIDE-A, A NEW CYTO-TOXIC DRUG ISOLATED FROM LISSOCLINUM BISTRATUM SLUITER [J].
GOUIFFES, D ;
MOREAU, S ;
HELBECQUE, N ;
BERNIER, JL ;
HENICHART, JP ;
BARBIN, Y ;
LAURENT, D ;
VERBIST, JF .
TETRAHEDRON, 1988, 44 (02) :451-459
[3]   BISTRAMIDE-A, A NEW TOXIN FROM THE UROCHORDATA LISSOCLINUM-BISTRATUM SLUITER - ISOLATION AND PRELIMINARY CHARACTERIZATION [J].
GOUIFFES, D ;
JUGE, M ;
GRIMAUD, N ;
WELIN, L ;
SAUVIAT, MP ;
BARBIN, Y ;
LAURENT, D ;
ROUSSAKIS, C ;
HENICHART, JP ;
VERBIST, JF .
TOXICON, 1988, 26 (12) :1129-1136
[4]  
GOUIFFES D, 1988, THESIS NANTES FRANCE
[5]  
GRIFFITHS DJ, 1987, SYMBIOSIS, V3, P109
[6]  
KOGURE K, 1989, 1ST P INT MARINE BIO
[7]  
KOTT P, 1984, B MAR SCI, V34, P308
[8]   PROCHLOROPHYTA AS A PROPOSED NEW DIVISION OF ALGAE [J].
LEWIN, RA .
NATURE, 1976, 261 (5562) :697-698
[9]  
MOORE RE, 1986, PURE APPL CHEM, V58, P2632
[10]  
MULLER WEG, 1984, BIOL CELL, V51, P381