MEASURED ENTROPY AND ENTHALPY OF HYDRATION AS A FUNCTION OF DISTANCE BETWEEN DNA DOUBLE HELICES

被引：85

作者：

LEIKIN, S ^{[1
]}

RAU, DC ^{[1
]}

PARSEGIAN, VA ^{[1
]}

机构：

[1] AN FRUMKIN ELECTROCHEM INST, MOSCOW, USSR

来源：

PHYSICAL REVIEW A | 1991年 / 44卷 / 08期

关键词：

D O I：

10.1103/PhysRevA.44.5272

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The temperature sensitivity of hydration forces between Mn2+-DNA helices in ordered arrays has been used to measure the entropic part of the interaction free-energy versus helix separation. This entropy is positive, and like the hydration force itself, grows exponentially as helices move closer. Measured forces show an abrupt transition between regions of interactions with quite different characteristic decay lengths, with a discontinuous change in interhelical spacing. However, both the entropic and enthalpic components of the interaction free-energy maintain smooth single-exponential variation across this transition.

引用

页码：5272 / 5278

页数：7

共 23 条

[1] THE FREE-ENERGY, ENTHALPY, AND ENTROPY OF HYDRATION OF PHOSPHOLIPID-BILAYER MEMBRANES AND THEIR DEPENDENCE ON THE INTERFACIAL SEPARATION [J].