PROPIONATE PRECURSORS IN THE BIOSYNTHESIS OF DAUNOMYCIN AND ADRIAMYCIN - C-13 NUCLEAR MAGNETIC-RESONANCE STUDY

被引：2

作者：

SHAW, GJ ^{[1
]}

MILNE, GWA ^{[1
]}

MINGHETTI, A ^{[1
]}

机构：

[1] FARMITALIA,RIC CHIM,I-20146 MILANO,ITALY

来源：

PHYTOCHEMISTRY | 1979年 / 18卷 / 01期

关键词：

!sup]13[!/sup]C-NMR; adriamycin; biosynthesis; daunomycin; sodium propionate[1-[!sup]13[!/sup]C; Streptomyces peucetius var. caesius;

D O I：

10.1016/S0031-9422(00)90943-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A 13C-NMR study of the biosynthesis of daunomycin adriamycin from propionate[1-13C] has been carried out in cultures of Streptomyces peucetius var. caesius. Results give direct support for the postulate that a propionate 'starter' is involved in the biosynthesis of both metabolites. © 1979.

引用

页码：178 / 179

页数：2

共 5 条

[1] ADRIAMYCIN, 14-HYDROXYDAUNOMYCIN, A NEW ANTITUMOR ANTIBIOTIC FROM S-PEUCETIUS VAR CAESIUS [J].