ISOLATION AND CHARACTERIZATION OF HIV-2BEN OBTAINED FROM A PATIENT WITH PREDOMINANTLY NEUROLOGICAL DEFECTS

被引：19

作者：

SCHNEIDER, J

LUKE, W

KIRCHHOFF, F

JUNG, R

JURKIEWICZ, E

STAHLHENNIG, C

NICK, S

KLEMM, E

JENTSCH, KD

HUNSMANN, G

机构：

[1] GERMAN PRIMATE CTR,W-3400 GOTTINGEN,GERMANY

[2] UNIV BONN,DEPT NEUROL,W-5300 BONN,GERMANY

来源：

AIDS | 1990年 / 4卷 / 05期

关键词：

HIV-2; Neurological defects;

D O I：

10.1097/00002030-199005000-00012

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A HIV-2 strain named HIV-2(ben) was isolated from peripheral blood lymphocytes of a patient who, since 1984, had developed neurological symptoms such as Raynaud's syndrome, followed by paresthesia of extremities and ataxia, and finally paraparesis of the legs and incontinence. This new isolate could be distinguished from HIV-2(rod) by antibody-binding epitopes, peptide maps of core p24 and p18 polypeptide and restriction endonuclease cleavage pattern.

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页码：455 / 457

页数：3

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