CYCLOPENTYLAMINE SUBSTITUTED TRIAZOLO[4,5-D]PYRIMIDINE - IMPLICATIONS FOR BINDING TO THE ADENOSINE RECEPTOR

被引：6

作者：

ESCHER, A

KENNARD, CHL

QUINN, RJ

SMITH, G

机构：

[1] GRIFFITH UNIV,SCH SCI,NATHAN,QLD 4111,AUSTRALIA

[2] UNIV QUEENSLAND,DEPT CHEM,BRISBANE 4072,AUSTRALIA

[3] QUEENSLAND UNIV TECHNOL,SCH CHEM,BRISBANE 4000,AUSTRALIA

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 29期

关键词：

D O I：

10.1016/0040-4039(91)80840-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-(3-chlorophenyl)-7-(N-cyclopentylamino)-5-methylthio-1,2,3-triazolo[4,5-d]pyrimidine was found to have restricted rotation around the exocyclic C-N bond. This has implications for the orientation of hydrophobic substituents relative to the plane of the heterocyclic ring of adenosine receptor ligands.

引用

页码：3583 / 3584

页数：2