The effect of B-vitamins on a swim-up syndrome in Lake Ontario lake trout

Collect ions of lake trout spawners and eggs were made in Lake Ontario to assess the ameliorative effects of several B-vitamins (thiamine, riboflavin, folic acid, nicotinic acid, pyridoxine hydrochloride) on mortality associated with swim-up syndrome. Vitamins were administered either by water immersion (I gm/L to eggs from one female) or intraperitoneal injection (30 ppm to eggs from five females) into the yolk sac. Thiamine, but none of the other B-vitamins, was effective both in reversal and prevention of the clinical signs and mortality associated with the syndrome.