CATECHOLAMINE-PROTEIN CONJUGATES - ISOLATION OF AN ADDUCT OF N-ACETYLHISTIDINE TO THE SIDE-CHAIN OF N-ACETYLDOPAMINE FROM AN INSECT-ENZYME CATALYZED REACTION

被引：22

作者：

ANDERSEN, SO

JACOBSEN, JP

ROEPSTORFF, P

PETER, MG

机构：

[1] UNIV ODENSE,DEPT CHEM,DK-5230 ODENSE,DENMARK

[2] UNIV ODENSE,DEPT MOLEC BIOL,DK-5230 ODENSE,DENMARK

[3] UNIV BONN,INST ORGAN CHEM & BIOCHEM,W-5300 BONN 1,GERMANY

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(00)92150-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-alpha-Acetyl-N-tau-[1-(3, 4-dihydroxyphenyl)-2-N-acetylamino-ethyl]-histidine (4) was isolated from a biomimetic reaction containing N-acetyl-dopamine 1, N-alpha-acetyl-L-histidine and cuticle of silkmoth larvae as an enzyme source. The formation of 4 suggests an 1,6-addition of the N-tau imidazole nitrogen to the p-quinone methide 3.

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页码：4287 / 4290

页数：4

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