THE GENE FOR LEUKOCYTE ANTIGEN-RELATED TYROSINE PHOSPHATASE (LAR) IS LOCALIZED TO HUMAN CHROMOSOME-1P32, A REGION FREQUENTLY DELETED IN TUMORS OF NEUROECTODERMAL ORIGIN

被引：13

作者：

JIRIK, FR

HARDER, KW

MELHADO, IG

ANDERSON, LL

DUNCAN, AMV

机构：

[1] UNIV BRITISH COLUMBIA,DEPT MED,VANCOUVER V6T 1W5,BC,CANADA

[2] QUEENS UNIV,DEPT PATHOL,KINGSTON K7L 3N6,ONTARIO,CANADA

来源：

CYTOGENETICS AND CELL GENETICS | 1992年 / 61卷 / 04期

关键词：

D O I：

10.1159/000133418

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In situ hybridization was employed to localize a cDNA probe from the human protein tyrosine phosphatase gene LAR to human metaphase chromosomes. LAR, a putative tumor suppressor gene, has been localized to 1p32, a chromosomal region that is frequently found deleted in human neuroblastoma and pheochromocytoma.

引用

页码：266 / 268

页数：3

共 17 条

[1] MOLECULAR-BIOLOGY AND GENETICS OF HUMAN NEURO-BLASTOMA
BRODEUR, GM
FONG, CT
[J]. CANCER GENETICS AND CYTOGENETICS, 1989, 41 (02) : 153 - 174
[2] COCKBURN DJ, 1991, CYTOGENET CELL GENET, V58, P1851
[3] DISTECHE CM, 1989, CYTOGENET CELL GENET, V51, P990
[4] PROTEIN TYROSINE PHOSPHATASES - A DIVERSE FAMILY OF INTRACELLULAR AND TRANSMEMBRANE ENZYMES
FISCHER, EH
CHARBONNEAU, H
TONKS, NK
[J]. SCIENCE, 1991, 253 (5018) : 401 - 406
[5] LOCALIZATION OF SINGLE COPY DNA-SEQUENCES ON G-BANDED HUMAN-CHROMOSOMES BY INSITU HYBRIDIZATION
HARPER, ME
SAUNDERS, GF
[J]. CHROMOSOMA, 1981, 83 (03) : 431 - 439
[6] A GUIDE TO FRAGILE SITES ON HUMAN-CHROMOSOMES
HECHT, F
RAMESH, KH
LOCKWOOD, DH
[J]. CANCER GENETICS AND CYTOGENETICS, 1990, 44 (01) : 37 - 45
[7] RECEPTOR PROTEIN-TYROSINE PHOSPHATASE-GAMMA IS A CANDIDATE TUMOR SUPPRESSOR GENE AT HUMAN-CHROMOSOME REGION 3P21
LAFORGIA, S
MORSE, B
LEVY, J
BARNEA, G
CANNIZZARO, LA
LI, F
NOWELL, PC
BOGHOSIANSELL, L
GLICK, J
WESTON, A
HARRIS, CC
DRABKIN, H
PATTERSON, D
CROCE, CM
SCHLESSINGER, J
HUEBNER, K
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (11) : 5036 - 5040
[8] HIGH-RESOLUTION CHROMOSOMAL LOCALIZATION OF THE BETA-GENE OF THE HUMAN BETA-GLOBIN GENE-COMPLEX BY INSITU HYBRIDIZATION
LIN, CC
DRAPER, PN
DEBRAEKELEER, M
[J]. CYTOGENETICS AND CELL GENETICS, 1985, 39 (04): : 269 - 274
[9] DELETION OF GENES ON CHROMOSOME-1 IN ENDOCRINE NEOPLASIA
MATHEW, CGP
SMITH, BA
THORPE, K
WONG, Z
ROYLE, NJ
JEFFREYS, AJ
PONDER, BAJ
[J]. NATURE, 1987, 328 (6130) : 524 - 526
[10] POT DA, 1991, J BIOL CHEM, V266, P19688

← 1 2 →