EFFECTS OF DIAZEPAM ON COGNITIVE-PROCESSES IN NORMAL SUBJECTS

被引：57

作者：

ROYBYRNE, PP

UHDE, TW

HOLCOMB, H

THOMPSON, K

KING, AK

WEINGARTNER, H

机构：

[1] NIMH, BIOL PSYCHIAT BRANCH, ANXIETY & AFFECT DISORDER UNIT, BLDG 10, BETHESDA, MD 20205 USA

[2] NIMH, CLIN SCI LAB, BETHESDA, MD 20205 USA

[3] NIMH, CEREBRAL METAB LAB, CLIN BRAIN IMAGING SECT, BETHESDA, MD 20205 USA

[4] NIMH, COGNIT STUDIES & HUMAN PERFORMANCE, BETHESDA, MD 20205 USA

来源：

PSYCHOPHARMACOLOGY | 1987年 / 91卷 / 01期

关键词：

D O I：

10.1007/BF00690922

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of 10 mg orally-administered diazepam on various aspects of cognition were examined in ten male subjects. Diazepam produced a subjective sense of cognitive impairment and impaired auditory vigilence, immediate recognition of twice presented words, a context-dependent free recall. There was a trend for a significant proportion of subjects to show impairment in delayed recognition of twice-presented words. There was no impairment of context-independent semantic memory, or of subjects'' ability to judge how well they had performed on the free recall task. In fact, subjects'' subjective sense of cognitive impairment was correlated with their performance on context-dependent memory tasks.

引用

页码：30 / 33

页数：4

共 17 条

[1] RECOGNITION AND RETRIEVAL PROCESSES IN FREE-RECALL [J].